On the flip side, there are some players that many were concerned about that may be ready to suit up.
For the Bucs, all the talk has been about rookie cornerback Jamel Dean, who left the game against the Jaguars early on and never returned. Dean was a full participant at practice Wednesday despite the shoulder injury.
Other notable Bucs listed were Demar Dotson (not injury related), Alex Cappa (elbow), Jason Pierre-Paul (knee), Scotty Miller (hamstring), and Anthony Nelson (knee) were all held out of practice while Jameis Winston (knee) and Chris Godwin (shin) were both full participants.
For Indianapolis, it appears as though running back Marlon Mack may be able to make his homecoming game a reality. Mack has missed the last few games with a broken hand but was a limited participant on Wednesday. And while receiver Parris Campbell was back and a full participant, T.Y. Hilton was held out and is doubtful for the game this week.
Here is the full injury report for each team;
The Buccaneers and Colts kick off this Sunday inside Raymond James Stadium at 1:00 p.m. ET.