The Bucs will see the return of rookie linebacker Devin White, coming off a knee injury, and cornerback Ryan Smith who is returning from suspension.
The Saints are still without future Hall of Fame quarterback Drew Brees who suffered a thumb injury in week two, but has begun throwing again in hopes that his return will be sooner than later.
Here are the full inactives for each team;
Tampa Bay Buccaneers:
Guard - Zack Bailey
Linebacker - Jack Cichy
Cornerback - Jamel Dean
Tackle - Jerald Hawkins
Tight End - Tanner Hudson
Defensive Lineman - Patrick O’Connor
Wide Receiver - Breshad Perriman
New Orleans Saints:
Quarterback - Drew Brees
Cornerback - Ken Crawley
Safety - Saquan Hampton
Guard - Nick Easton
Offensive Lineman - Ethan Greenidge
Wide Receiver - Lil’Jordan Humphrey
Defensive End - Trey Hendrickson
The Buccaneers will be using a rotation of Bobo Wilson, Justin Watson, and Scotty Miller to replace Perriman who is out with a hamstring issue while cornerback Jamel Dean is missing his second game in a row.
The Bucs and Saints kick off at 1:00 p.m. EST in New Orleans.