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The Tampa Bay Buccaneers and San Francisco 49ers haven't exactly been injury-free this season, but both teams appear to be fairly healthy heading into Sunday's contest.
Mario Manningham and Mike Iupati represent the most significant injuries for either team. Manningham has been out for most of the season with an injury catching just 8 passes on the season. His possible absence doesn't need to be a big issue for a San Francisco team that has done well with and without him. Iupati is a lot more important to the 49ers, especially to their run game. If he can't go, Gerald McCoy should have a field day in the run and pass game against the 49ers.
The Tampa Bay Buccaneers are likely to be entirely healthy, except for Carl Nicks who once again won't suit up. With just two games after Sunday, Nicks is probably not returning to action this year even though the Buccaneers have clearly held out hope so far.
Buccaneers injury report
| Name | Pos. | Injury | Wednesday | Thursday | Friday | Status |
| Nicks, Carl | G | Foot | DNP | DNP | DNP | Out |
| Bowers, Da'Quan | DE | Knee | DNP | Limited | Full | Probable |
| David, Lavonte | LB | Back | Full | Full | Full | Probable |
| Gholston, William | DE | Head | Full | Full | Full | Probable |
| Gibson, Gary | DT | Calf | Full | Full | Full | Probable |
| Jackson, Vincent | WR | Hamstring | DNP | Limited | Full | Probable |
| Joseph, Davin | G | Knee/Shoulder | DNP | Full | Full | Probable |
| Spence, Akeem | DT | Wrist | Full | Full | Full | Probable |
| Zuttah, Jeremy | C | Shoulder | DNP | Limited | Full | Probable |
49ers injury report
| Name | Pos. | Injury | Wednesday | Thursday | Friday | Status |
| Brown, Tarell | CB | Ribs | Limited | Limited | Limited | Questionable |
| Iupati, Mike | G | Knee | Limited | Limited | Limited | Questionable |
| Manningham, Mario | WR | Knee | Limited | Limited | Limited | Questionable |
| McDonald, Vance | TE | Ankle | Limited | Limited | Limited | Questionable |
| Baldwin, Jon | WR | Shoulder | Full | Full | Probable | |
| Crabtree, Michael | WR | Ankle | Limited | Limited | Full | Probable |
| Dahl, Craig | S | Ankle | Limited | Limited | Full | Probable |
| Gore, Frank | RB | Ankle | Limited | Limited | Full | Probable |
| McDonald, Ray | DT | Ankle | DNP | Limited | Full | Probable |
| Skuta, Dan | LB | Foot | Limited | Limited | Full | Probable |
| Smith, Aldon | LB | Shoulder | Full | Full | Full | Probable |
| Smith, Justin | DT | Shoulder | DNP | Limited | Full | Probable |
| Snyder, Adam | G | Not Injury Rel. | DNP | Full | Full | Probable |
| Staley, Joe | T | Knee | Full | Full | Full | Probable |
