The Bucs don't believe Nicks will be sidelined for an extended period. He and fellow Pro Bowl G Davin Joseph haven't taken a snap together— Ira Kaufman (@IKaufmanTBO) August 22, 2013
Initial reports suggested the All-Pro guard could miss around a month of playing time, which would keep him out for two or three regular season games. We'll see whether that holds up, but it's almost certain he doesn't play in the preseason. But at least he's responding to treatment, now.
If Nicks is to miss time, Ted Larsen or Gabe Carimi could see some playing time at left guard, while center Jeremy Zuttah could slide over to that spot as well. The Bucs have some options there, but you can't ever replace an All-Pro guard, only mitigate his absence.